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Thirteen Anonymous Genetic Superheroes Walk Among Us—Or Do They? – The Atlantic.

“The idea came from frustration and unfulfilled quests,” says Friend, a physician at the Icahn School of Medicine at Mount Sinai. For decades, he had watched geneticists trying to find the genes that underlie diseases as diverse as cystic fibrosis, Alzheimer’s disease, and schizophrenia. Such studies have been undoubtedly successful, but the growing list of culprit genes have rarely led to treatments for their respective disorders.

“I had an a-ha moment,” says Friend. “If you want to find a way of preventing disease, you shouldn’t be looking at people with the disease. “You should look at people who should have been sick but aren’t.”

Read more & visit The Resilience Project.


“Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases” @ Nature. There is a re-contact clause so no one can contact the 13 “super heros” “The more we sequence, the more we need to sequence.”